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What's New

Welcome to the What’s New? section of our Web site. Here you will find the latest information about our products, our application notes and support materials, our annual biocalorimetry conference, and our company. Please bookmark this page and visit often to see the latest information from MicroCal.

The new MicroCal™ Auto-iTC200 Software 1.1 improves data quality and saves time with automated data analysis

MicroCal™ Auto-iTC200 Software

The new MicroCal Auto-iTC200 Software 1.1 provides improved data quality, robust automated data analysis and more flexible operation.

  • New optimized automation scripts give improved performance and assay reliability
  • More robust data analysis minimize the need to make manual adjustments to the data
  • An improved Baseline Adjustment Tool is even easier to use if manual adjustments are desired
  • When doing assay development, the user has the capability to interrupt the current experiment and skip to the next to save time and sample
  • A new data analysis model has been added for weak binding applications

For more information about the new software, please contact your local representative.

The new MicroCal™ VP-Capillary DSC Software 2.0 brings a new level of productivity to automated DSC.

MicroCal™ VP-Capillary DSC

The new MicroCal VP-Capillary DSC Software 2.0 streamlines the experiment workflow with improved experimental design and setup. Flexible instrument scheduling further enhances efficiency in multi-user laboratory environments. Automated data analysis and improved data sorting reduce the time spent analysing data and generating results from days to hours. Baselines and buffer subtraction are automated to give more consistent results from run to run. Key results, such as Tm, Tm onset, T1/2, ΔTm, and ΔH are automatically calculated and tabulated.

For more information about the new software, please contact your local representative.

 

Journal Citations for iTC200 and
Auto-iTC200 Click here »

 

ITC Application notes

28-9870-38         
Revealing Kinase Inhibitor Mechanisms

28-9870-43       
The use of ITC for obtaining enzyme kinetic constants

28-9870-44       
Studying low-affinity fragments of ligands by ITC

DSC Application notes

28-9870-36        
DSC theory and practice

28-9870-37        
DSC in the development of liquid formulations for protein biopharmaceuticals

28-9870-39        
Shelf-life determination of low molecular weight compounds

28-9870-40        
Usage of DSC for more economical process development

28-9870-41        
Development and Optimization of protein formulations

28-9870-42        
Using DSC to understand the correlation between thermal stability and protein stability

28-9870-45        
Better guidance in antibody therapeutics process development using DSC

28-9870-46        
Differential factors that contribute to the intrinsic and designed stability of antibody Fab regions

Cleaning Instructions

28-9897-40
MicroCal VP-DSC and VP-Capillary DSC Cleaning Instructions

Bia2iTC Software

The new Bia2iTC (beta release) software for integrated use of Biacore & Microcal systems facilitates the use of Biacore affinity data to optimize experimental design in complementary MicroCal assays. To learn more click here.

Training

Practical and theoretical courses are available on the use of MicroCal systems. Participants receive personal support and comprehensive course literature. For more information on our training courses, please contact us at microcaltraining@ge.com.